The effect of administration of 11 b-hydroxyandrostenedione in feed on morphology of some internal organs of wels, Silurus glanis (L.)

Abstract

Studies were carried out on the effect of a natural androgen, 11 b-hyroxyandrostenedione (OHA) administrated in feed on morphology of some internal organs of wels, Silurus glanis (L.). No distinct masculinization or adverse impact of the hormone on gonads was observed. No pathological changes were noted in the kidneys, liver or skin. Statistically significant increase of hepatocyte size, epidermis thickness, and - in some individuals – hyperplasia and increase of circumglomerulal space in kidneys were observed only in the group treated with 50 mg of OHA per kg of feed.